Epstein-Barr virus evades restrictive host chromatin closure by subverting B cell activation and germinal center regulatory loci
Summary: Chromatin accessibility fundamentally governs gene expression and biological response programs that can be manipulated by pathogens.Here we capture dynamic chromatin landscapes of individual B cells during Epstein-Barr virus (EBV) infection.EBV+ cells that exhibit arrest via antiviral sensing and proliferation-linked DNA damage experience